Journal: EJNMMI Radiopharmacy and Chemistry
Article Title: Exploring the theranostic potential of two metabolically stable GRPR-targeting peptides labelled with Ga-68 for PET imaging
doi: 10.1186/s41181-026-00431-5
Figure Lengend Snippet: In vitro binding specificity ( A ) and cellular internalization ( B ) of [ 68 Ga]Ga-AU-RM26-M2 (black), [ 68 Ga]Ga-PKB2 (blue), and [ 68 Ga]Ga-PKB3 (red) in PC-3 cells. Representative competition binding curves for nat Ga-AU-RM26-M2, nat Ga-PKB2, and nat Ga-PKB3 against [ 125 I]I-Tyr 4 -BBN in PC-3 cells ( C ). Error bars could not be visible due to low variability. Data are presented as mean ± SD, n = 3 for A and B ; n = 6 for C
Article Snippet: The human GRPR-positive prostate cancer cell line (PC-3) was purchased from American Type Culture Collection (Manassas, VA, USA).
Techniques: In Vitro, Binding Assay